UPO book

Brief Research Description

The main research fields are:

1. Molecular genetics of B cell neoplasia, with a particular focus on chronic lymphocytic leukemia and B-cell non-Hodgkin lymphoma

2. Molecular basis of disease dissemination in lymphoid malignancies, aiming at understanding the mechanisms of progression and localization at multiple sites of B cell lymphoproliferative disorders

3. Identification of molecular predictors of chronic lymphocytic leukemia and of B cell non-Hodgkin lymphoma, in order to refine a Precision Medicine approach for the clinical management of these neoplasms

4. Participation of clinical trials of novel therapeutic approaches for hematologic malignancies, with a particular focus on target therapies with small molecules and immunotherapy with bispecific antibodies and drug-immunoconjugates for B cell malignancies

5. Liquid biopsy in lymphoma, aiming at defining a non-invasive approach for predicting outcome and monitoring minimal residual disease in aggressive lymphoma, with a specific focus on diffuse large B-cell lymphoma

Keywords

chronic lymphocytic leukemia, lymphoma, molecular predictors, liquid biopsy, precision medicine 

PubMed