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Research Activity
Research Activity
Brief Research Description
Pathogenic mechanisms of Acute Kidney Injury (AKI): role of plasma extracellular vesicles (EVs) and Gram negative-derived LPS and Quorum Sensing.
AKI to Chronic Kidney Disease (CKD) transition: biomarker discover studies and identification of pathways involved in the progression from AKI to CKD. Development of drugs able to interfere with kidney aging.
Extracorporeal Blood Purification Therapies in sepsis-induced AKI: protective role of different types of membranes and devices able to enhance the clearance of detrimental humoral mediators.
Inflammation in chronic hemodialysis patients: role of uremic toxins in early vascular aging, cardiovascular events and cognitive decline.
New therapeutic approaches to limit ischemia-reperfusion injury (IRI), viral infections and rejection in kidney transplantation.
Protective role of stem cell-derived extracellular vesicles in experimental models of AKI, glomerular diseases and kidney transplantation.
Keywords
Acute Kidney Injury, kidney transplantation, extracorporeal blood purification therapies, extracellular vesicles, kidney aging.
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